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Observe Intently (one)pentobarbital will reduce the extent or outcome of buprenorphine subdermal implant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Carefully. Watch clients by now on buprenorphine subdermal implant who have to have freshly-initiated treatment with CYP3A4 inducer for signs and signs of w

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